Visual Neglect and Orienting Bias in Right Hemisphere Stroke Patients with and without Thrombolysis (Pehmeäkantinen kirja)

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Thrombolysis is standard pharmacological treatment for patients with acute ischemic stroke. It significantly improves outcome when administered within three hours of stroke onset. However, knowledge remains limited about the frequency and severity of cognitive disorders after thrombolytic treatment at the acute phase of right hemisphere stroke. To help fill this knowledge gap, the present series of studies explores the association between visual neglect and thrombolytic treatment, focusing specifically on rightward orienting bias, one of the main manifestations of visual neglect. In addition, it reviews the various methods used in assessing visual neglect.

The review in Study I demonstrated differences in the accuracy of the methods used. There were also differences in patient selection and the timing of assessments of visual neglect. Neglect was assessed with a wide variety of tests. A standardized battery of neglect tests was administered in 16 studies, while four studies used two or more separate tasks. Only four studies made a distinction between subtypes of neglect. The reported prevalence of neglect is probably affected by the range of assessment methods used.
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