The Dynamic Universe theory is a holistic description of the observable physical reality. It is a unifying theory converting spacetime in variable coordinates into dynamic space in absolute coordinates. The Dynamic Universe theory relies on an overall zero-energy balance in space and the conservation of the total energy in interactions in space. Predictions for local phenomena in DU space are essentially the same as the corresponding predictions given by the special and general theories of relativity. At extremes - at cosmological distances and in the vicinity of local singularities in space - differences in the predictions become meaningful, e.g. the Dynamic Universe theory, in a perfect agreement with observations, predicts Euclidean appearance of galaxy sizes, and provides a precise prediction to magnitude versus redshift observations without postulating dark energy or accelerating expansion of space. "The Dynamic Universe, Toward a unified picture of physical reality" gives a detailed introduction of the Dynamic Universe theory from its philosophical basis to predictions and comparisons to prevailing theories and observations.